Jennifer Tsai

Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point

Rachel Darman, Michael Seiler, Anant A. Agrawal et al. · Cell Reports · 2015 · 463 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites

Min Yu, T. R. Santha Kumar, Louis J. Nkrumah et al. · Cell Host & Microbe · 2008 · 319 citations · Full text

Life Sciences, Biochemistry, Molecular Genetics +12

Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex

Teng Teng, Jennifer Tsai, Xiaoling Puyang et al. · Nature Communications · 2017 · 149 citations · Full text

Life Sciences, Biology, Molecular Biology +16

The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action

Lorenzo I. Finci, Xiaofeng Zhang, Xiuliang Huang et al. · Genes & Development · 2018 · 112 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +16

Mycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosis

Amanda J. Martinot, Mary F. Farrow, Lu Bai et al. · PLoS Pathogens · 2016 · 105 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17