Kwan Leung

Studies on the Metabolism of Troglitazone to Reactive Intermediates in Vitro and in Vivo. Evidence for Novel Biotransformation Pathways Involving Quinone Methide Formation and Thiazolidinedione Ring Scission

Kelem Kassahun, Paul G. Pearson, Wei Tang et al. · Chemical Research in Toxicology · 2000 · 307 citations

Medicine, Pharmacology, Toxicology +14

Bioavailability Improvement of Mycophenolic Acid Through Amino Ester Derivatization

William A. Lee, Leo Gu, Andrew R. Miksztal et al. · Pharmaceutical Research · 1990 · 260 citations

Pharmacy, Pharmacokinetics, Pharmacology +12

Studies on Cytochrome P-450-Mediated Bioactivation of Diclofenac in Rats and in Human Hepatocytes: Identification of Glutathione Conjugated Metabolites

Wei Tang, Ralph A. Stearns, Stelvio M. Bandiera et al. · Drug Metabolism and Disposition · 1999 · 170 citations

Pharmacy, Pharmacology, Toxicology +17

Determination ofin vitro permeability of drug candidates through a Caco-2 cell monolayer by liquid chromatography/tandem mass spectrometry

Zhen Wang, Cornelis E. C. A. Hop, Kwan Leung et al. · Journal of Mass Spectrometry · 2000 · 103 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +17

Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use–dependent inhibitor of dopamine synthesis

Lina Yao, Peidong Fan, María Pía Arolfo et al. · Nature Medicine · 2010 · 98 citations · Full text

Medicine, Neuroscience, Pharmacology +16