William A. Lee

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

Travis K. Warren, Robert Jordan, Michael K. Lo et al. · Nature · 2016 · 1.6K citations · Full text

Small Molecule Gs-5734, Rhesus Monkeys, Medicine +10

Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-<i>f</i>][triazin-4-amino] Adenine <i>C</i>-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses

Dustin S. Siegel, Hon C. Hui, Edward Doerffler et al. · Journal of Medicinal Chemistry · 2017 · 648 citations · Full text

Selective Intracellular Activation of a Novel Prodrug of the Human Immunodeficiency Virus Reverse Transcriptase Inhibitor Tenofovir Leads to Preferential Distribution and Accumulation in Lymphatic Tissue

William A. Lee, Gong-Xin He, Eugene Eisenberg et al. · Antimicrobial Agents and Chemotherapy · 2005 · 337 citations · Full text

Bioavailability Improvement of Mycophenolic Acid Through Amino Ester Derivatization

William A. Lee, Leo Gu, Andrew R. Miksztal et al. · Pharmaceutical Research · 1990 · 258 citations

TLR7 agonists induce transient viremia and reduce the viral reservoir in SIV-infected rhesus macaques on antiretroviral therapy

So‐Yon Lim, Christa E. Osuna, Peter Hraber et al. · Science Translational Medicine · 2018 · 158 citations · Full text