Dustin S. Siegel - Concepedia

Concepedia

Author

Dustin S. Siegel

Gilead Sciences (United States)ORCID

Also Known As

Clarke, Michael O., D Siegel, D. Siegel, Dustin S. Siegel, Dustin Siegel, Siegel, Dustin, Siegel, Dustin S., Sims, Amy C., Sunkyu Han

43

Publications

6.6K

Citations

15

H-Index

29

Concepts

All Affiliations

Gilead Sciences (United States)Massachusetts Institute of Technology Centers for Disease Control and Prevention Vanderbilt University Medical Center United States Army Medical Research Institute of Infectious Diseases

DS

About

Dustin S. Siegel is an author at Gilead Sciences (United States) specializing in medicine, virology, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	7	7	1.9K
2	Natural Sciences	4	4	122
3	Biochemistry	2	2	37
4	Engineering	1	1	100
5	Chemical Biology	1	1	12

Dustin S. Siegel

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18

Publications

6.6K

Citations

15

H-Index

	Year	Citations
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses Timothy P. Sheahan, Amy Sims, Rachel L. Graham, Science Translational Medicine	2017	1.6K
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys Travis K. Warren, Robert Jordan, Michael K. Lo, Nature Small Molecule Gs-5734Rhesus MonkeysMedicineViral PathogenesisImmunology	2016	1.6K
Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease Maria L. Agostini, Erica L. Andres, Amy Sims, mBio	2018	1.5K
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-<i>f</i>][triazin-4-amino] Adenine <i>C</i>-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses Dustin S. Siegel, Hon C. Hui, Edward Doerffler, Journal of Medicinal Chemistry	2017	648
GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses Michael K. Lo, Robert Jordan, Aaron Arvey, Scientific Reports	2017	504
Discovery of an Oral Respiratory Syncytial Virus (RSV) Fusion Inhibitor (GS-5806) and Clinical Proof of Concept in a Human RSV Challenge Study Richard L. Mackman, Michael Sangi, David Sperandio, Journal of Medicinal Chemistry ImmunologyPharmacologyRsv InfectionVirologyClinical Proof	2015	120
C7-Derivatization of C3-Alkylindoles Including Tryptophans and Tryptamines Richard P. Loach, Owen S. Fenton, Kazuma Amaike, The Journal of Organic Chemistry C3-alkylindoles Including TryptophansChemical EngineeringCross-coupling ReactionEngineeringC7-selective Boronation	2014	100
Total synthesis of all (−)-agelastatin alkaloids Mohammad Movassaghi, Dustin S. Siegel, Sunkyu Han Chemical Science	2010	90
Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi® James G. Taylor, Sheila Zipfel, Kyla Ramey, Bioorganic & Medicinal Chemistry Letters Molecular VirologyViral HepatitisImmunologyAntiviral Drug DevelopmentHepatitis	2019	83
Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine <i>C</i>-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV Richard L. Mackman, Hon C. Hui, Michel Perron, Journal of Medicinal Chemistry	2021	79

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