Kelem Kassahun

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

Daria J. Hazuda, Neville J. Anthony, Robert Gomez et al. · Proceedings of the National Academy of Sciences · 2004 · 332 citations · Full text

Hiv-1 Integrase, Immunology, Cell Culture +17

Studies on the Metabolism of Troglitazone to Reactive Intermediates in Vitro and in Vivo. Evidence for Novel Biotransformation Pathways Involving Quinone Methide Formation and Thiazolidinedione Ring Scission

Kelem Kassahun, Paul G. Pearson, Wei Tang et al. · Chemical Research in Toxicology · 2000 · 306 citations

Troglitazone Undergoes Metabolism, Pharmaceutical Science, Thiazolidinedione Ring Scission +16

Metabolism and Disposition in Humans of Raltegravir (MK-0518), an Anti-AIDS Drug Targeting the Human Immunodeficiency Virus 1 Integrase Enzyme

Kelem Kassahun, Ian McIntosh, Donghui Cui et al. · Drug Metabolism and Disposition · 2007 · 274 citations

In Vitro and in Vivo Evaluation of Dihydropyrimidinone C-5 Amides as Potent and Selective α_1A Receptor Antagonists for the Treatment of Benign Prostatic Hyperplasia

James C. Barrow, Philippe G. Nantermet, Harold G. Selnick et al. · Journal of Medicinal Chemistry · 2000 · 220 citations · Full text

Molecular Pharmacology, Urology, Pharmacological Study +12

Disposition and biotransformation of the antipsychotic agent olanzapine in humans.

Kelem Kassahun, Edward L. Mattiuz, Eldon H. Nyhart et al. · PubMed · 1997 · 212 citations

Plasma Compartment, Psychotropic Medication, Psychopharmacology +18