Kelem Kassahun

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

Daria J. Hazuda, Neville J. Anthony, Robert Gomez et al. · Proceedings of the National Academy of Sciences · 2004 · 333 citations · Full text

Life Sciences, Pharmacokinetics, Pharmacology +17

Studies on the Metabolism of Troglitazone to Reactive Intermediates in Vitro and in Vivo. Evidence for Novel Biotransformation Pathways Involving Quinone Methide Formation and Thiazolidinedione Ring Scission

Kelem Kassahun, Paul G. Pearson, Wei Tang et al. · Chemical Research in Toxicology · 2000 · 307 citations

Medicine, Pharmacology, Toxicology +14

Metabolism and Disposition in Humans of Raltegravir (MK-0518), an Anti-AIDS Drug Targeting the Human Immunodeficiency Virus 1 Integrase Enzyme

Kelem Kassahun, Ian McIntosh, Donghui Cui et al. · Drug Metabolism and Disposition · 2007 · 275 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

In Vitro and in Vivo Evaluation of Dihydropyrimidinone C-5 Amides as Potent and Selective α_1A Receptor Antagonists for the Treatment of Benign Prostatic Hyperplasia

James C. Barrow, Philippe G. Nantermet, Harold G. Selnick et al. · Journal of Medicinal Chemistry · 2000 · 223 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Disposition and biotransformation of the antipsychotic agent olanzapine in humans.

Kelem Kassahun, Edward L. Mattiuz, Eldon H. Nyhart et al. · PubMed · 1997 · 212 citations

Medicine, Pharmacokinetics, Pharmacology +15