Paul G. Pearson

Acalabrutinib (ACP-196): A Covalent Bruton Tyrosine Kinase Inhibitor with a Differentiated Selectivity and In Vivo Potency Profile

Tjeerd Barf, Todd Covey, Raquel Izumi et al. · Journal of Pharmacology and Experimental Therapeutics · 2017 · 370 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Glucuronidation of Statins in Animals and Humans: A Novel Mechanism of Statin Lactonization

Thomayant Prueksaritanont, Raju Subramanian, Xiaojun Fang et al. · Drug Metabolism and Disposition · 2002 · 346 citations

Medicine, Biochemistry, Pharmacology +13

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

Daria J. Hazuda, Neville J. Anthony, Robert Gomez et al. · Proceedings of the National Academy of Sciences · 2004 · 333 citations · Full text

Life Sciences, Pharmacokinetics, Pharmacology +17

Studies on the Metabolism of Troglitazone to Reactive Intermediates in Vitro and in Vivo. Evidence for Novel Biotransformation Pathways Involving Quinone Methide Formation and Thiazolidinedione Ring Scission

Kelem Kassahun, Paul G. Pearson, Wei Tang et al. · Chemical Research in Toxicology · 2000 · 307 citations

Medicine, Pharmacology, Toxicology +14

Mechanistic Studies on Metabolic Interactions between Gemfibrozil and Statins

Thomayant Prueksaritanont, Jamie J. Zhao, Bennett Ma et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 288 citations

Pharmacy, Pharmacokinetics, Pharmacology +14