Concepedia

Mechanistic Studies on Metabolic Interactions between Gemfibrozil and Statins

Thomayant Prueksaritanont, Jamie J. Zhao, Bennett Ma, Brad Roadcap, Cuyue Tang, Yue Qiu, Lida Liu, Jiunn H. Lin, Paul G. Pearson, Thomas A. Baillie

Journal of Pharmacology and Experimental Therapeutics · 2002 · 288 citations · 26 references

DOI

Concepts

References

26

Preclinical and clinical pharmacology of rosuvastatin, a new 3-hydroxy- 3-methylglutaryl coenzyme A reductase inhibitor11CRESTOR is a trademark, the property of AstraZeneca PLC. Research discussed in this article was supported by AstraZeneca.

Fergus McTaggart, Linda K. Buckett, Robert G. Davidson et al. · The American Journal of Cardiology · 2001 · 415 citations

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Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole*

Pertti J. Neuvonen, Teemu Kantola, Kari T. Kivistö · Clinical Pharmacology & Therapeutics · 1998 · 403 citations

, , +11

Human Serum Paraoxonase (pon1) Isozymes Q and R Hydrolyze Lactones and Cyclic Carbonate Esters

Scott S. Billecke, Dragomir Draganov, Raymond E. Counsell et al. · Drug Metabolism and Disposition · 2000 · 400 citations

, , +11

Glucuronidation of Statins in Animals and Humans: A Novel Mechanism of Statin Lactonization

Thomayant Prueksaritanont, Raju Subramanian, Xiaojun Fang et al. · Drug Metabolism and Disposition · 2002 · 346 citations

, , +13

In Vitro Glucuronidation Using Human Liver Microsomes and The Pore-Forming Peptide Alamethicin

Michael B. Fisher, Kristina Campanale, Bradley L. Ackermann et al. · Drug Metabolism and Disposition · 2000 · 342 citations

, , +14