Donghui Cui

Discovery of the Dual Orexin Receptor Antagonist [(7<i>R</i>)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2<i>H</i>-1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the Treatment of Insomnia

Christopher D. Cox, Michael J. Breslin, David B. Whitman et al. · Journal of Medicinal Chemistry · 2010 · 370 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +12

Metabolism and Disposition in Humans of Raltegravir (MK-0518), an Anti-AIDS Drug Targeting the Human Immunodeficiency Virus 1 Integrase Enzyme

Kelem Kassahun, Ian McIntosh, Donghui Cui et al. · Drug Metabolism and Disposition · 2007 · 275 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Promotion of Sleep by Suvorexant—A Novel Dual Orexin Receptor Antagonist

Christopher J. Winrow, Anthony L. Gotter, Christopher D. Cox et al. · Journal of Neurogenetics · 2011 · 270 citations

Medicine, Neuroscience, Pharmacology +16

Metabolism and Disposition of Dasatinib after Oral Administration to Humans

Lisa J. Christopher, Donghui Cui, Chi‐Yuan Wu et al. · Drug Metabolism and Disposition · 2008 · 197 citations

Medicine, Pharmacokinetics, Pharmacology +13

Discovery of [(2<i>R</i>,5<i>R</i>)‐5‐{[(5‐Fluoropyridin‐2‐yl)oxy]methyl}‐2‐methylpiperidin‐1‐yl][5‐methyl‐2‐(pyrimidin‐2‐yl)phenyl]methanone (MK‐6096): A Dual Orexin Receptor Antagonist with Potent Sleep‐Promoting Properties

Paul J. Coleman, John D. Schreier, Christopher D. Cox et al. · ChemMedChem · 2012 · 124 citations

Medicine, Medicinal Chemistry, Pharmacology +17