Ralph A. Stearns

A role for the melanocortin 4 receptor in sexual function

Lex H.T. Van der Ploeg, William J. Martin, Andrew D. Howard et al. · Proceedings of the National Academy of Sciences · 2002 · 301 citations

Life Sciences, Neuroscience, Physiology +17

Biotransformation of losartan to its active carboxylic acid metabolite in human liver microsomes. Role of cytochrome P4502C and 3A subfamily members.

Ralph A. Stearns, Probir Chakravarty, R Chen et al. · Drug Metabolism and Disposition · 1995 · 208 citations

Medicine, Biochemistry, Pharmacology +17

Design and Pharmacology of <i>N</i>-[(3<i>R</i>)-1,2,3,4-Tetrahydroisoquinolinium- 3-ylcarbonyl]-(1<i>R</i>)-1-(4-chlorobenzyl)- 2-[4-cyclohexyl-4-(1<i>H</i>-1,2,4-triazol- 1-ylmethyl)piperidin-1-yl]-2-oxoethylamine (<b>1</b>), a Potent, Selective, Melanocortin Subtype-4 Receptor Agonist

Iyassu K. Sebhat, William J. Martin, Zhixiong Ye et al. · Journal of Medicinal Chemistry · 2002 · 193 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Studies on Cytochrome P-450-Mediated Bioactivation of Diclofenac in Rats and in Human Hepatocytes: Identification of Glutathione Conjugated Metabolites

Wei Tang, Ralph A. Stearns, Stelvio M. Bandiera et al. · Drug Metabolism and Disposition · 1999 · 170 citations

Pharmacy, Pharmacology, Toxicology +17

Extrapolation of Diclofenac Clearance from in Vitro Microsomal Metabolism Data: Role of Acyl Glucuronidation and Sequential Oxidative Metabolism of the Acyl Glucuronide

Sanjeev Kumar, Koppara Samuel, Matthew P. Braun et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 165 citations

Pharmacy, Pharmacokinetics, Pharmacology +17