Iyassu K. Sebhat - Concepedia

Author

Iyassu K. Sebhat

Merck & Co., Inc., Rahway, NJ, USA (United States)ORCID

Also Known As

I. K. SEBHAT, I. K. Sebhat, I. Sebhat, Iyassu K. Sebhat, Iyassu Sebhat, Sebhat, I.K.

Publications

1.9K

Citations

H-Index

Concepts

All Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)Albany Molecular Research (United States)The University of Texas at Austin Imperial College London

About

Iyassu K. Sebhat is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in pharmacology, medicine, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	17	21	1.5K
2	Natural Sciences	12	12	558
3	Engineering	1	1	20
4	Health Sciences	1	1	41
5	Social Sciences	1	1	298

Iyassu K. Sebhat

Publications

1.7K

Citations

H-Index

Page 1

	Year	Citations
Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy Robert W. Myers, Hong-Ping Guan, Juliann Ehrhart, Science Cardiac MuscleCardiovascular PharmacologyGlucose HomeostasisMetabolic RemodelingCardiovascular Function	2017	329
A role for the melanocortin 4 receptor in sexual function Lex H.T. Van der Ploeg, William J. Martin, Andrew D. Howard, Proceedings of the National Academy of Sciences Erectile DysfunctionFood IntakeReproductive BiologySocial SciencesHypothalamic Peptide	2002	298
Design and Pharmacology of <i>N</i>-[(3<i>R</i>)-1,2,3,4-Tetrahydroisoquinolinium- 3-ylcarbonyl]-(1<i>R</i>)-1-(4-chlorobenzyl)- 2-[4-cyclohexyl-4-(1<i>H</i>-1,2,4-triazol- 1-ylmethyl)piperidin-1-yl]-2-oxoethylamine (<b>1</b>), a Potent, Selective, Melanocortin Subtype-4 Receptor Agonist Iyassu K. Sebhat, William J. Martin, Zhixiong Ye, Journal of Medicinal Chemistry Erectile DysfunctionFood IntakePeptide SciencePharmacotherapyExperimental Pharmacology	2002	190
Synthesis of the Antitumor Alkaloid (+)-Pancratistatin Using the β-Azidonation Reaction via a Prochiral 4-Arylcyclohexanone Derivative Philip Magnus, Iyassu K. Sebhat Journal of the American Chemical Society Bioorganic ChemistryAltmetric Attention ScoreDerivativephilip Magnusβ-Azidonation ReactionPharmaceutical Chemistry	1998	87
Activation of melanocortin MC4 receptors increases erectile activity in rats ex copula William J. Martin, Erin McGowan, Doreen E. Cashen, European Journal of Pharmacology Erectile DysfunctionMedicineErectile ActivityPhysiologySexual Dysfunction	2002	82
Application of the β-azidonation reaction to the synthesis of the antitumor alkaloid (+)-pancratistatin Philip Magnus, Iyassu K. Sebhat Tetrahedron Medicinal ChemistryMedicineAnti-cancer Agentβ-Azidonation ReactionDrug Development	1998	67
Discovery of MK-5046, a Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity Iyassu K. Sebhat, Christopher S. Franklin, Michael M.‐C. Lo, ACS Medicinal Chemistry Letters ObesityCompound 22BiochemistryFunctional SelectivityMedicine	2010	65
Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase Danqing Feng, Tesfaye Biftu, F. Anthony Romero, ACS Medicinal Chemistry Letters Early Generation CompoundsMetabolic RemodelingInsulin SignalingMetabolic SyndromeMolecular Pharmacology	2017	56
Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis Ji Zhang, Eric S. Muise, Seongah Han, Cell Reports Medicine	2020	52
Antiobesity Effect of MK-5046, a Novel Bombesin Receptor Subtype-3 Agonist Xiao-Ming Guan, Joseph M. Metzger, Liming Yang, Journal of Pharmacology and Experimental Therapeutics	2010	49

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