Marie-Louise Smith

Cellular pharmacology and in vivo activity of a new anticancer agent, ZD9331: a water-soluble, nonpolyglutamatable, quinazoline-based inhibitor of thymidylate synthase.

Ann L. Jackman, Rosemary Kimbell, G. Wynne Aherne et al. · PubMed · 1997 · 92 citations

Medicine, Oncology, Pharmacology +13

Discovery of 6-Phenylpyrimido[4,5-<i>b</i>][1,4]oxazines as Potent and Selective Acyl CoA:Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitors with in Vivo Efficacy in Rodents

Brian M. Fox, Kazuyuki Sugimoto, Kiyosei Iio et al. · Journal of Medicinal Chemistry · 2014 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Use of Murine L5178Y Lymphoma Thymidine Kinase Mutants for in Vitro and in Vivo Antitumour Efficacy Evaluation of Novel Thymidylate Synthase Inhibitors

T C Stephens, Marie-Louise Smith, S. E. Waterman et al. · Advances in experimental medicine and biology · 1993 · 13 citations

Medicine, Oncology, Pharmacology +6

Substituted-2-Desamino-2-Methyl-Quinazolinones. A Series of Novel Antitumour Agents

F.T. Boyle, Zbigniew S. Matusiak, L. R. HUGHES et al. · Advances in experimental medicine and biology · 1993 · 11 citations

Pharmacy, Medicinal Chemistry, Pharmacology +4

A novel series of IKKβ inhibitors part I: Initial SAR studies of a HTS hit

Timothy D. Cushing, Vijay Baichwal, Karen Berry et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 10 citations

Pharmacy, Medicinal Chemistry, Pharmacology +5