Brian M. Fox

Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development

Daqing Sun, Zhihong Li, Yosup Rew et al. · Journal of Medicinal Chemistry · 2014 · 290 citations · Full text

Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction

Yosup Rew, Daqing Sun, Felix González-López de Turiso et al. · Journal of Medicinal Chemistry · 2012 · 166 citations · Full text

Synthesis of New Indeno[1,2-<i>c</i>]isoquinolines:  Cytotoxic Non-Camptothecin Topoisomerase I Inhibitors

Mark Cushman, Muthusamy Jayaraman, Jeffrey A. Vroman et al. · Journal of Medicinal Chemistry · 2000 · 163 citations

Synthesis of New Dihydroindeno[1,2-<i>c</i>]isoquinoline and Indenoisoquinolinium Chloride Topoisomerase I Inhibitors Having High in Vivo Anticancer Activity in the Hollow Fiber Animal Model

Muthusamy Jayaraman, Brian M. Fox, Melinda G. Hollingshead et al. · Journal of Medicinal Chemistry · 2001 · 94 citations

Medicinal Chemistry, Vivo Anticancer Activity, Natural Product Synthesis +12

Design, Synthesis, and Biological Evaluation of Cytotoxic 11-Alkenylindenoisoquinoline Topoisomerase I Inhibitors and Indenoisoquinoline−Camptothecin Hybrids

Brian M. Fox, Xiangshu Xiao, Smitha Antony et al. · Journal of Medicinal Chemistry · 2003 · 92 citations