Mark Cushman - Concepedia

Author

Mark Cushman

Purdue University West Lafayette ORCID

Also Known As

Cushman, M., Cushman, Mark, M Cushman, M. CUSHMAN, M. Cushman, M.D. Feese, MARK CUSHMAN, Mark Cushman, Mark S. Cushman

316

Publications

9.8K

Citations

H-Index

113

Concepts

All Affiliations

Purdue University West Lafayette Center for Cancer Research National Cancer Institute National Institutes of Health

About

Mark Cushman is an author at Purdue University West Lafayette specializing in pharmacology, medicine, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	39	74	3.4K
2	Natural Sciences	33	68	2.7K
3	Engineering	19	26	853
4	Health Sciences	6	6	458
5	Arts	1	1	36

Mark Cushman

176

Publications

9.5K

Citations

H-Index

Page 1

	Year	Citations
Structures of Three Classes of Anticancer Agents Bound to the Human Topoisomerase I−DNA Covalent Complex Bart L. Staker, M.D. Feese, Mark Cushman, Journal of Medicinal Chemistry	2005	527
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization Mark Cushman, Dhanapalan Nagarathnam, Dhanushya Gopal, Journal of Medicinal Chemistry	1991	297
Synthesis, Antitubulin and Antimitotic Activity, and Cytotoxicity of Analogs of 2-Methoxyestradiol, an Endogenous Mammalian Metabolite of Estradiol That Inhibits Tubulin Polymerization by Binding to the Colchicine Binding Site Mark Cushman, Hu-Ming He, John A. Katzenellenbogen, Journal of Medicinal Chemistry	1995	185
Protein-Linked DNA Strand Breaks Induced by NSC 314622, a Novel Noncamptothecin Topoisomerase I Poison Glenda Kohlhagen, Kenneth D. Paull, Mark Cushman, Molecular Pharmacology	1998	167
Synthesis of New Indeno[1,2-<i>c</i>]isoquinolines: Cytotoxic Non-Camptothecin Topoisomerase I Inhibitors Mark Cushman, Muthusamy Jayaraman, Jeffrey A. Vroman, Journal of Medicinal Chemistry	2000	163
A novel norindenoisoquinoline structure reveals a common interfacial inhibitor paradigm for ternary trapping of the topoisomerase I-DNA covalent complex Christophe Marchand, Smitha Antony, Kurt W. Kohn, Molecular Cancer Therapeutics	2006	161
The indenoisoquinoline noncamptothecin topoisomerase I inhibitors: update and perspectives Yves Pommier, Mark Cushman Molecular Cancer Therapeutics Chemoprevention StrategyPharmacotherapyHistone H2axPharmaceutical ChemistryTumor Biology	2009	153
Synthesis and protein-tyrosine kinase inhibitory activities of flavonoid analogs Mark Cushman, Dhanapalan Nagarathnam, Debra L. Burg, Journal of Medicinal Chemistry	1991	152
Synthesis of Cytotoxic Indenoisoquinoline Topoisomerase I Poisons Dirk Strumberg, Yves Pommier, Kenneth D. Paull, Journal of Medicinal Chemistry	1999	133
Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Topoisomerase I Inhibitors Featuring Polyamine Side Chains on the Lactam Nitrogen Muthukaman Nagarajan, Xiangshu Xiao, Smitha Antony, Journal of Medicinal Chemistry	2003	129

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