Glenda Kohlhagen

Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA.

Myoung Sook Kim, Mellissa Blake, Jin Hyen Baek et al. · PubMed · 2003 · 464 citations

Medicine, Oncology, Pharmacology +15

DNA Sequence- and Structure-Selective Alkylation of Guanine N2 in the DNA Minor Groove by Ecteinascidin 743, a Potent Antitumor Compound from the Caribbean Tunicate <i>Ecteinascidia turbinata</i>

Yves Pommier, Glenda Kohlhagen, Christian Bailly et al. · Biochemistry · 1996 · 299 citations

Life Sciences, Biochemistry, Molecular Biology +16

Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells.

Mariafiorella Brangi, Thomas Litman, Marco Ciotti et al. · PubMed · 1999 · 261 citations

Medicine, Oncology, Pharmacology +15

Early Induction of Apoptosis in Hematopoietic Cell Lines After Exposure to Flavopiridol

Bernard W. Parker, Gurmeet Kaur, Wilberto Nieves‐Neira et al. · Blood · 1998 · 226 citations · Full text

Life Sciences, Hematology, Pharmacology +11

Human mitochondrial topoisomerase I

Hongliang Zhang, Juana Barceló, Benson Lee et al. · Proceedings of the National Academy of Sciences · 2001 · 214 citations · Full text

Life Sciences, Genetics, Molecular Biology +8