G. Wynne Aherne

bcl-2 modulation of apoptosis induced by anticancer drugs: resistance to thymidylate stress is independent of classical resistance pathways.

Thomas C. Fisher, Anne E. Milner, C D Gregory et al. · PubMed · 1993 · 237 citations

Medicine, Oncology, Pharmacology +17

Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity

Lindsay Stimson, Martin Rowlands, Yvette Newbatt et al. · Molecular Cancer Therapeutics · 2005 · 222 citations · Full text

Medicine, Oncology, Pharmacology +13

The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors

Kwai-Ming J. Cheung, Thomas P. Matthews, Karen James et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 219 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

The relevance of the presence of certain synthetic steroids in the aquatic environment

G. Wynne Aherne, Ray J. Briggs · Journal of Pharmacy and Pharmacology · 1989 · 187 citations

Natural Sciences, Environmental Sciences, Toxicology +16

The bioavailability and pharmacokinetics of morphine after intravenous, oral and buccal administration in healthy volunteers.

GW Hanks, G. Wynne Aherne, Daniel P. Chapman et al. · British Journal of Clinical Pharmacology · 1989 · 170 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +15