Karen James

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

Suzanne A. Eccles, Andy Massey, Florence I. Raynaud et al. · Cancer Research · 2008 · 469 citations

4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer

Paul A. Brough, Wynne Aherne, Xavier Barril et al. · Journal of Medicinal Chemistry · 2007 · 442 citations · Full text

The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors

Kwai-Ming J. Cheung, Thomas P. Matthews, Karen James et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 219 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +10

Short-term safety outcomes of mastectomy and immediate implant-based breast reconstruction with and without mesh (iBRA): a multicentre, prospective cohort study

Shelley Potter, Elizabeth J. Conroy, Ramsey I Cutress et al. · The Lancet Oncology · 2019 · 188 citations · Full text

Inhibition of the heat shock protein 90 molecular chaperone <i>in vitro</i> and <i>in vivo</i> by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues

Swee Y. Sharp, Chrisostomos Prodromou, Kathy Boxall et al. · Molecular Cancer Therapeutics · 2007 · 142 citations