Suzanne A. Eccles

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Georgios Vlachogiannis, Somaieh Hedayat, Alexandra Vatsiou et al. · Science · 2018 · 2.1K citations · Full text

Medicine, Oncology, Pharmacology +17

A microRNA DNA methylation signature for human cancer metastasis

Amaia Lujambio, George A. Calin, Alberto Villanueva et al. · Proceedings of the National Academy of Sciences · 2008 · 1.1K citations · Full text

Medicine, Cancer Biology, Oncology +17

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

Maria Vinci, Sharon Gowan, Frances Boxall et al. · BMC Biology · 2012 · 1K citations · Full text

Medicine, Cell Biology, Oncology +17

The Identification of 2-(1<i>H</i>-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-<i>d</i>]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer

Adrian Folkes, Khatereh Ahmadi, W. Alderton et al. · Journal of Medicinal Chemistry · 2008 · 746 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Dual Targeting of ErbB2 and MUC1 in Breast Cancer Using Chimeric Antigen Receptors Engineered to Provide Complementary Signaling

Scott Wilkie, May CI van Schalkwyk, Steve Hobbs et al. · Journal of Clinical Immunology · 2012 · 484 citations

Medicine, Cancer Biology, Oncology +12