Somaieh Hedayat

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Georgios Vlachogiannis, Somaieh Hedayat, Alexandra Vatsiou et al. · Science · 2018 · 2.1K citations · Full text

Medicine, Oncology, Pharmacology +17

Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial

Khurum Khan, David Cunningham, Benjamin Werner et al. · Cancer Discovery · 2018 · 237 citations · Full text

Medicine, Molecular Biology, Oncology +17

MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma

Andrea Lampis, Pietro Carotenuto, Georgios Vlachogiannis et al. · Gastroenterology · 2017 · 113 citations · Full text

Medicine, Oncology, Pharmacology +17

Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells

Roberta Ferraldeschi, Jonathan Welti, Marissa Powers et al. · Cancer Research · 2016 · 91 citations · Full text

Life Sciences, Endocrinology, Oncology +8

Functional imaging and circulating biomarkers of response to regorafenib in treatment-refractory metastatic colorectal cancer patients in a prospective phase II study

Khurum Khan, Mihaela Rata, David Cunningham et al. · Gut · 2017 · 72 citations · Full text

Medicine, Oncology, Radiology +17