Identification of neutral tumor evolution across cancer types

Marc Williams, Benjamin Werner, C. Barnes, +2

Nature Genetics

Tumor BiologyTumor HeterogeneityMedicineNeutral Tumor EvolutionPathology +4

Quantification of subclonal selection in cancer from bulk sequencing data

Marc Williams, Benjamin Werner, Timon Heide, +4

Nature Genetics

Tumor BiologyOncologyTumor HeterogeneityMedicinePathology +10

Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial

Khurum Khan, David Cunningham, Benjamin Werner, +33

Cancer Discovery

The evolutionary dynamics of extrachromosomal DNA in human cancers

Joshua T. Lange, John C. Rose, Celine Chen, +19

Nature Genetics

Phenotypic plasticity and genetic control in colorectal cancer evolution

Jacob Househam, Timon Heide, George D. Cresswell, +30

Nature

Evolutionary dynamics of neoantigens in growing tumors

Eszter Lakatos, Marc Williams, Ryan O. Schenck, +10

Nature Genetics

Pattern FormationEvolutionary DynamicsTumor HeterogeneityEvolutionary BiologyMedicine +3

Subclonal reconstruction of tumors by using machine learning and population genetics

Giulio Caravagna, Timon Heide, Marc Williams, +12

Nature Genetics

Radiation OncologyEngineeringMachine LearningMedical ImagingTumor Heterogeneity +7

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

Ahmet Acar, Daniel Nichol, Javier Fernández-Mateos, +16

Nature Communications

Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions

Benjamin Werner, Fabian Beier, Sebastian Hummel, +6

eLife

Adult Stem CellStem Cell BehaviorStem Cell MobilizationHematologyBiostatistics +15

Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data

Ketevan Chkhaidze, Timon Heide, Benjamin Werner, +5

PLoS Computational Biology

Tumour GrowthSignificant Sampling BiasesTumor BiologyTumor HeterogeneitySingle Cell Sequencing +16