Sharon Gowan

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

Maria Vinci, Sharon Gowan, Frances Boxall et al. · BMC Biology · 2012 · 1K citations · Full text

Medicine, Cell Biology, Oncology +17

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

Suzanne A. Eccles, Andy Massey, Florence I. Raynaud et al. · Cancer Research · 2008 · 478 citations · Full text

Medicine, Oncology, Pharmacology +8

Pharmacologic Characterization of a Potent Inhibitor of Class I Phosphatidylinositide 3-Kinases

Florence I. Raynaud, Suzanne A. Eccles, Paul A. Clarke et al. · Cancer Research · 2007 · 352 citations · Full text

Medicine, Oncology, Pharmacology +10

A G-Quadruplex-Interactive Potent Small-Molecule Inhibitor of Telomerase Exhibiting in Vitro and in Vivo Antitumor Activity

Sharon Gowan, John Harrison, Lisa Patterson et al. · Molecular Pharmacology · 2002 · 289 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941

Florence I. Raynaud, Suzanne A. Eccles, Sonal Patel et al. · Molecular Cancer Therapeutics · 2009 · 274 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14