A G-Quadruplex-Interactive Potent Small-Molecule Inhibitor of Telomerase Exhibiting in Vitro and in Vivo Antitumor Activity

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

Education, Cell Biology, Molecular Biology +15

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse et al. · Science · 1994 · 7.1K citations

Life Sciences, Cell Biology, Oncology +16

Telomeres shorten during ageing of human fibroblasts

Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature · 1990 · 5.7K citations

Education, Cell Biology, Genetics +11

The RNA Component of Human Telomerase

Junli Feng, Walter D. Funk, Sy-Shi Wang et al. · Science · 1995 · 2.2K citations

Life Sciences, Genetics, Molecular Biology +13

hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization

Matthew Meyerson, Christopher M. Counter, Elinor Ng Eaton et al. · Cell · 1997 · 1.8K citations · Full text

Life Sciences, Genetics, Molecular Biology +11