Concepedia

Telomere Maintenance

Telomere Maintenance is a molecular mechanism that preserves the integrity and length of telomeric DNA at chromosome ends through specialized enzymatic activities, primarily involving telomerase or alternative lengthening pathways, to counteract replicative shortening and maintain genomic stability.

5.6K

Publications

514K

Citations

24.6K

Authors

3.8K

Institutions

Publications per year

2017–2026

1K

Parents

Children

Publications

5.6K

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse et al. · Science · 1994 · 7.1K citations

, , +16

Telomeres shorten during ageing of human fibroblasts

Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature · 1990 · 5.7K citations

, , +11

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

Carol W. Greider, Elizabeth H. Blackburn · Cell · 1985 · 3.4K citations · Full text

, , +11

A DNA damage checkpoint response in telomere-initiated senescence

Fabrizio d’Adda di Fagagna, Philip M. Reaper, Lorena Clay-Farrace et al. · Nature · 2003 · 2.8K citations

, , +14

Oxidative stress shortens telomeres

Thomas von Zglinicki · Trends in Biochemical Sciences · 2002 · 2.5K citations

, , +12

1–5 of 5.6K

Authors

24.6K

  1. MA
    Marı́a A. Blasco

    Spanish National Cancer Research Centre, Spain

    90 publications · 17.1K citations

    64

    h-index

  2. JW
    Jerry W. Shay

    The University of Texas Southwestern Medical Center, United States

    109 publications · 23.5K citations

    64

    h-index

  3. EH
    Elizabeth H. Blackburn

    University of California, San Francisco, United States

    81 publications · 19.2K citations

    57

    h-index

  4. TD
    Titia de Lange

    Rockefeller University, United States

    68 publications · 21.9K citations

    57

    h-index

  5. WE
    Woodring E. Wright

    The University of Texas Southwestern Medical Center, United States

    76 publications · 19.5K citations

    55

    h-index

1–5 of 24.6K

Institutions

3.8K

  1. The University of Texas Southwestern Medical Center

    Dallas, United States

    74 h-index

    527 publications

    105.9K citations

  2. Harvard University

    Cambridge, United States

    72 h-index

    551 publications

    96.3K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    68 h-index

    294 publications

    82.1K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    68 h-index

    785 publications

    64.7K citations

  5. Johns Hopkins University

    Baltimore, United States

    67 h-index

    491 publications

    101.8K citations

  6. University of California, San Francisco

    San Francisco, United States

    66 h-index

    479 publications

    65.2K citations

  7. National Institutes of Health

    Bethesda, United States

    65 h-index

    576 publications

    67K citations

  8. Rockefeller University

    New York, United States

    63 h-index

    251 publications

    81K citations

1–8 of 3.8K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 156 publications · 24.4K citations

    88

    h-index

  2. Cell

    89 publications · 38.9K citations

    85

    h-index

  3. Molecular and Cellular Biology

    MCB · 169 publications · 18K citations

    79

    h-index

  4. The EMBO Journal

    109 publications · 17.3K citations

    73

    h-index

  5. Nature

    72 publications · 39.6K citations

    66

    h-index

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