Concepedia
Statistics
Publications
48
Citations
4.1K
H-Index
32
Active since
1957
Affiliations
Institute of Cancer Research(Current)
Cancer Research UK
University of Surrey
University College London
Royal Marsden Hospital
Wynne Aherne is an author at Institute of Cancer Research specializing in medicine, pharmacology, and cancer research.
Top concepts
MedicinePharmacologyCancer ResearchBiochemistryDrug DiscoveryNatural SciencesMolecular BiologyOncologyPathologyBioanalysis
Publications per year
1957–2015
NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis
Suzanne A. Eccles, Andy Massey, Florence I. Raynaud et al. · Cancer Research · 2008 · 469 citations
4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer
Paul A. Brough, Wynne Aherne, Xavier Barril et al. · Journal of Medicinal Chemistry · 2007 · 442 citations · Full text
Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms
Lisa Wright, Xavier Barril, Brian Dymock et al. · Chemistry & Biology · 2004 · 265 citations · Full text
Hsp90 Isoforms, Signal Transduction, Biochemistry +5
Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response
Maruf M. U. Ali, Tina Bagratuni, Emma L. Davenport et al. · The EMBO Journal · 2011 · 246 citations · Full text
Protein Function, Signal Transduction, Biochemistry +9
High-throughput screening assay for inhibitors of heat-shock protein 90 ATPase activity
Martin Rowlands, Yvette Newbatt, Chrisostomos Prodromou et al. · Analytical Biochemistry · 2004 · 194 citations
Atpase Activity, Cellular Enzymology, Biochemistry +10
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