Martin Rowlands

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

Suzanne A. Eccles, Andy Massey, Florence I. Raynaud et al. · Cancer Research · 2008 · 478 citations · Full text

Medicine, Oncology, Pharmacology +8

Novel Steroidal Inhibitors of Human Cytochrome P45017.alpha.-Hydroxylase-C17,20-lyase): Potential Agents for the Treatment of Prostatic Cancer

Gerard A. Potter, S. Elaine Barrie, Michael Jarman et al. · Journal of Medicinal Chemistry · 1995 · 380 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response

Maruf M. U. Ali, Tina Bagratuni, Emma L. Davenport et al. · The EMBO Journal · 2011 · 252 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity

Lindsay Stimson, Martin Rowlands, Yvette Newbatt et al. · Molecular Cancer Therapeutics · 2005 · 222 citations · Full text

Medicine, Oncology, Pharmacology +13

The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors

Kwai-Ming J. Cheung, Thomas P. Matthews, Karen James et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 219 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14