Concepedia
Statistics
Publications
64
Citations
4.7K
H-Index
37
Active since
1994
Affiliations
National University of Singapore(Current)
Singapore Science Park
Institute of Cancer Research
National University Health System
Cancer Research UK
Brian Dymock is an author at National University of Singapore specializing in medicine, pharmacology, and drug discovery.
Top concepts
MedicinePharmacologyDrug DiscoveryMedicinal ChemistryBiochemistryNatural SciencesChemical BiologyCell SignalingCell BiologyPharmacotherapy
Publications per year
1994–2019
NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis
Suzanne A. Eccles, Andy Massey, Florence I. Raynaud et al. · Cancer Research · 2008 · 469 citations
4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer
Paul A. Brough, Wynne Aherne, Xavier Barril et al. · Journal of Medicinal Chemistry · 2007 · 442 citations · Full text
Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms
Lisa Wright, Xavier Barril, Brian Dymock et al. · Chemistry & Biology · 2004 · 265 citations · Full text
Hsp90 Isoforms, Signal Transduction, Biochemistry +5
Novel, Potent Small-Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered through Structure-Based Design
Brian Dymock, Xavier Barril, Paul A. Brough et al. · Journal of Medicinal Chemistry · 2005 · 231 citations · Full text
Crystal Structure, Drug Target, Molecular Biology +18
SB1518, a novel macrocyclic pyrimidine-based JAK2 inhibitor for the treatment of myeloid and lymphoid malignancies
Stefan Hart, K C Goh, Veronica Novotny‐Diermayr et al. · Leukemia · 2011 · 195 citations · Full text
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