Concepedia

Brian Dymock

BD

64

Publications

4.7K

Citations

37

H-Index

1994

Active since

Affiliations

National University of Singapore(Current)

Singapore Science Park

Institute of Cancer Research

National University Health System

Cancer Research UK

Brian Dymock is an author at National University of Singapore specializing in medicine, pharmacology, and drug discovery.

ORCID

Top concepts

Publications per year

1994–2019

64

Publications

64

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

Suzanne A. Eccles, Andy Massey, Florence I. Raynaud et al. · Cancer Research · 2008 · 469 citations

4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer

Paul A. Brough, Wynne Aherne, Xavier Barril et al. · Journal of Medicinal Chemistry · 2007 · 442 citations · Full text

Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms

Lisa Wright, Xavier Barril, Brian Dymock et al. · Chemistry & Biology · 2004 · 265 citations · Full text

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Novel, Potent Small-Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered through Structure-Based Design

Brian Dymock, Xavier Barril, Paul A. Brough et al. · Journal of Medicinal Chemistry · 2005 · 231 citations · Full text

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SB1518, a novel macrocyclic pyrimidine-based JAK2 inhibitor for the treatment of myeloid and lymphoid malignancies

Stefan Hart, K C Goh, Veronica Novotny‐Diermayr et al. · Leukemia · 2011 · 195 citations · Full text

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