Stefan Hart

TACE cleavage of proamphiregulin regulates GPCR‐induced proliferation and motility of cancer cells

Andreas Gschwind, Stefan Hart, Oliver M. Fischer et al. · The EMBO Journal · 2003 · 341 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +11

Cannabinoids Induce Cancer Cell Proliferation via Tumor Necrosis Factor α-Converting Enzyme (TACE/ADAM17)-Mediated Transactivation of the Epidermal Growth Factor Receptor

Stefan Hart, Oliver M. Fischer, Axel Ullrich · Cancer Research · 2004 · 287 citations

Medicine, Oncology, Pharmacology +14

SB1518, a novel macrocyclic pyrimidine-based JAK2 inhibitor for the treatment of myeloid and lymphoid malignancies

Stefan Hart, K C Goh, Veronica Novotny‐Diermayr et al. · Leukemia · 2011 · 199 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Discovery of the Macrocycle 11-(2-Pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene (SB1518), a Potent Janus Kinase 2/Fms-Like Tyrosine Kinase-3 (JAK2/FLT3) Inhibitor for the Treatment of Myelofibrosis and Lymphoma

Anthony D. William, Angeline C.-H. Lee, Stéphanie Blanchard et al. · Journal of Medicinal Chemistry · 2011 · 198 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention

Han Kiat Ho, Sharon Pok, Sylvia Streit et al. · Journal of Hepatology · 2008 · 194 citations

Medicine, Molecular Biology, Oncology +11