Concepedia

TACE cleavage of proamphiregulin regulates GPCR‐induced proliferation and motility of cancer cells

Andreas Gschwind, Stefan Hart, Oliver M. Fischer, A. Ullrich

The EMBO Journal · 2003 · 341 citations · 43 references

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43

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.4K citations

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An Essential Role for Ectodomain Shedding in Mammalian Development

Jacques J. Peschon, Jennifer L. Slack, P. Linga Reddy et al. · Science · 1998 · 1.6K citations

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EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

Norbert Prenzel, Esther Zwick, Henrik Daub et al. · Nature · 1999 · 1.5K citations

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Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

Henrik Daub, Christian Wallasch, Axel Ullrich · Nature · 1996 · 1.5K citations

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Prostaglandin E2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy

Rama Pai, Brian Soreghan, Imre Szabó et al. · Nature Medicine · 2002 · 833 citations

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