Prostaglandin E2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy

Rama Pai, Brian Soreghan, Imre Szabó, +3

Nature Medicine

Prostaglandin E2Gastrointestinal OncologyGastrointestinal PharmacologyColon Cancer GrowthGastroenterology +8

Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models

Luc Desnoyers, Rama Pai, Ronald E. Ferrando, +8

Oncogene

OncologyMedicineCancer GrowthPathologyFibroblast Growth Factor +6

Expression of heme oxygenase-1 in atherosclerotic lesions.

Li-Jen Wang, Tzong‐Shyuan Lee, Fan-Yen Lee, +2

PubMed

Pharmacological Characterization of Human and Murine Neuropeptide S Receptor Variants

Rainer K. Reinscheid, Yanling Xu, Naoe Okamura, +5

Journal of Pharmacology and Experimental Therapeutics

PGE2 Stimulates VEGF Expression in Endothelial Cells via ERK2/JNK1 Signaling Pathways

Rama Pai, Imre Szabó, Brian A. Soreghan, +3

Biochemical and Biophysical Research Communications

Endothelial Cell PathobiologyDevelopmental BiologyAngiogenesisSignal TransductionEndothelial Cells +10

Deoxycholic Acid Activates β-Catenin Signaling Pathway and Increases Colon Cell Cancer Growth and Invasiveness

Rama Pai, Andrzej S. Tarnawski, Teresa Tran

Molecular Biology of the Cell

Tumor BiologyGastrointestinal OncologyMedicinePharmacologySecondary Bile Acids +11

Prostaglandins promote colon cancer cell invasion; signaling by cross‐talk between two distinct growth factor receptors

Rama Pai, Toshikazu Nakamura, Woo Sung Moon, +1

The FASEB Journal

Tumor BiologyChemoprevention StrategyGrowth FactorMedicineColorectal Cancer +11

Inhibition of Fibroblast Growth Factor 19 Reduces Tumor Growth by Modulating β-Catenin Signaling

Rama Pai, Debra Dunlap, Jing Qing, +3

Cancer Research

PathologyCell ProliferationCancer BiologyTumor BiologySignaling Pathway +14

Induction of mitogen-activated protein kinase signal transduction pathway during gastric ulcer healing in rats

Rama Pai, Masayuki Ohta, Rabiha M. Itani, +2

Gastroenterology

InflammationSignal TransductionSignaling PathwayReceptor Tyrosine KinasePhysiology +10

Gene therapy for gastric ulcers with single local injection of naked DNA encoding VEGF and angiopoietin-1

Michael K. Jones, Hirofumi Kawanaka, Dolgor Baatar, +7

Gastroenterology

Single Local InjectionNovel TherapyIn Vivo Gene TherapyPathologyNaked Dna +5