Concepedia

Angeline C.-H. Lee

AC

Statistics

Publications

5

Citations

377

H-Index

5

Active since

2010

Affiliations

Singapore Science Park(Current)

Angeline C.-H. Lee is an author at Singapore Science Park specializing in pharmacology, medicinal chemistry, and tyrosine kinase inhibitors.

Publications per year

2010–2012

5

Publications

5

Discovery of the Macrocycle 11-(2-Pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene (SB1518), a Potent Janus Kinase 2/Fms-Like Tyrosine Kinase-3 (JAK2/FLT3) Inhibitor for the Treatment of Myelofibrosis and Lymphoma

Anthony D. William, Angeline C.-H. Lee, Stéphanie Blanchard et al. · Journal of Medicinal Chemistry · 2011 · 198 citations · Full text

, , +17

Discovery of Kinase Spectrum Selective Macrocycle (16<i>E</i>)-14-Methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a Potent Inhibitor of Cyclin Dependent Kinases (CDKs), Janus Kinase 2 (JAK2), and Fms-like Tyrosine Kinase-3 (FLT3) for the Treatment of Cancer

Anthony D. William, Angeline C.-H. Lee, Kee Chuan Goh et al. · Journal of Medicinal Chemistry · 2011 · 100 citations · Full text

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Discovery of the Macrocycle (9<i>E</i>)-15-(2-(Pyrrolidin-1-yl)ethoxy)-7,12,25-trioxa-19,21,24-triaza-tetracyclo[18.3.1.1(2,5).1(14,18)]hexacosa-1(24),2,4,9,14(26),15,17,20,22-nonaene (SB1578), a Potent Inhibitor of Janus Kinase 2/Fms-LikeTyrosine Kinase-3 (JAK2/FLT3) for the Treatment of Rheumatoid Arthritis

Anthony D. William, Angeline C.-H. Lee, Anders Poulsen et al. · Journal of Medicinal Chemistry · 2012 · 52 citations · Full text

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Synthesis and evaluation of alkenyl indazoles as selective Aurora kinase inhibitors

Stéphanie Blanchard, Anthony D. William, Angeline C.-H. Lee et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 17 citations · Full text

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Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as PDK1 inhibitors discovered by fragment-based screening

Angeline C.-H. Lee, Pondy Murugappan Ramanujulu, Anders Poulsen et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 10 citations · Full text

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