Kee Chuan Goh

Regulation of c‐myc expression by IFN‐γ through Stat1‐dependent and ‐independent pathways

Chilakamarti V. Ramana, Nicholas Grammatikakis, Mikhail Chernov et al. · The EMBO Journal · 2000 · 323 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Discovery of the Macrocycle 11-(2-Pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene (SB1518), a Potent Janus Kinase 2/Fms-Like Tyrosine Kinase-3 (JAK2/FLT3) Inhibitor for the Treatment of Myelofibrosis and Lymphoma

Anthony D. William, Angeline C.-H. Lee, Stéphanie Blanchard et al. · Journal of Medicinal Chemistry · 2011 · 198 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

SIRT1 Modulating Compounds from High-Throughput Screening as Anti-Inflammatory and Insulin-Sensitizing Agents

Vasantha M. Nayagam, Xukun Wang, Yong Tan et al. · SLAS DISCOVERY · 2006 · 147 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

SB939, a Novel Potent and Orally Active Histone Deacetylase Inhibitor with High Tumor Exposure and Efficacy in Mouse Models of Colorectal Cancer

Veronica Novotny‐Diermayr, Kanda Sangthongpitag, Chang Hu et al. · Molecular Cancer Therapeutics · 2010 · 132 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +12

Discovery of Kinase Spectrum Selective Macrocycle (16<i>E</i>)-14-Methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a Potent Inhibitor of Cyclin Dependent Kinases (CDKs), Janus Kinase 2 (JAK2), and Fms-like Tyrosine Kinase-3 (FLT3) for the Treatment of Cancer

Anthony D. William, Angeline C.-H. Lee, Kee Chuan Goh et al. · Journal of Medicinal Chemistry · 2011 · 100 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16