Pondy Murugappan Ramanujulu

Design and Synthesis of Ligand Efficient Dual Inhibitors of Janus Kinase (JAK) and Histone Deacetylase (HDAC) Based on Ruxolitinib and Vorinostat

Lianbin Yao, Nurulhuda Mustafa, Eng Chong Tan et al. · Journal of Medicinal Chemistry · 2017 · 101 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Design and Synthesis of Janus Kinase 2 (JAK2) and Histone Deacetlyase (HDAC) Bispecific Inhibitors Based on Pacritinib and Evidence of Dual Pathway Inhibition in Hematological Cell Lines

Eugene Guorong Yang, Nurulhuda Mustafa, Eng Chong Tan et al. · Journal of Medicinal Chemistry · 2016 · 90 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Discovery of New H₂S Releasing Phosphordithioates and 2,3-Dihydro-2-phenyl-2-sulfanylenebenzo[<i>d</i>][1,3,2]oxazaphospholes with Improved Antiproliferative Activity

Feng Wei, Xin-Yi Teo, Wisna Novera et al. · Journal of Medicinal Chemistry · 2015 · 87 citations

Medicine, Medicinal Chemistry, Pharmacology +8

An improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo

Hiu Yeung Lau, Pondy Murugappan Ramanujulu, Dianyan Guo et al. · Cancer Biology & Therapy · 2014 · 63 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Functionalized indoleamines as potent, drug-like inhibitors of isoprenylcysteine carboxyl methyltransferase (Icmt)

Pondy Murugappan Ramanujulu, Tianming Yang, Siew-Qi Yap et al. · European Journal of Medicinal Chemistry · 2013 · 28 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9