Experimental Drug Development Centre

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

Kyle J. Roux, Dae In Kim, Manfred Raida et al. · The Journal of Cell Biology · 2012 · 2.5K citations · Full text

Interacting Proteins, Systems Biology, Protein Function +15

Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis

Wen Cai Zhang, Ng Shyh‐Chang, Yang He et al. · Cell · 2012 · 666 citations · Full text

Glycine Decarboxylase Activity, Oncogenic Agent, Medicine +7

Identification of Molecular Subtypes of Gastric Cancer With Different Responses to PI3-Kinase Inhibitors and 5-Fluorouracil

Zhengdeng Lei, Iain Beehuat Tan, Kakoli Das et al. · Gastroenterology · 2013 · 443 citations · Full text

Molecular Subtypes, Gastrointestinal Oncology, Medicine +9

Wnt addiction of genetically defined cancers reversed by PORCN inhibition

Babita Madan, Zhanbo Ke, Nathan Harmston et al. · Oncogene · 2015 · 339 citations · Full text

Porcn Inhibition, Pathology, Wnt Addiction +16

Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants

Ilyas Chachoua, C. Pecquet, Mira El-Khoury et al. · Blood · 2015 · 327 citations · Full text