Amy M. Delaney

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

Jeffrey F. Ohren, Huifen Chen, A.G. Pavlovsky et al. · Nature Structural & Molecular Biology · 2004 · 621 citations

Life Sciences, Biochemistry, Molecular Biology +9

The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901

Stephen D. Barrett, Alexander J. Bridges, David T. Dudley et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 286 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor

Andrea J. Gonzales, Kenneth E. Hook, Irene W. Althaus et al. · Molecular Cancer Therapeutics · 2008 · 221 citations · Full text

Medicine, Oncology, Pharmacology +15

Activation of the Unfolded Protein Response via Inhibition of Protein Disulfide Isomerase Decreases the Capacity for DNA Repair to Sensitize Glioblastoma to Radiotherapy

Yajing Liu, Wenbin Ji, Andrea Shergalis et al. · Cancer Research · 2019 · 73 citations · Full text

Medicine, Molecular Biology, Oncology +14

Identification of a Novel Mitogen-Activated Protein Kinase Kinase Activation Domain Recognized by the Inhibitor PD 184352

Amy M. Delaney, John A. Printen, Huifen Chen et al. · Molecular and Cellular Biology · 2002 · 72 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15