Concepedia

Irene W. Althaus

IW

Statistics

Publications

19

Citations

2.4K

H-Index

16

Active since

1988

Affiliations

W.E. Upjohn Institute for Employment Research(Current)

Pfizer (United States)

University of Michigan

Cancer Society of New Zealand

University of Auckland

Irene W. Althaus is an author at W.E. Upjohn Institute for Employment Research specializing in enzyme inhibition, life sciences, and molecular biology.

Publications per year

1988–2021

19

Publications

19

PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with <i>EGFR</i> and <i>ERBB2</i> Mutations that Are Resistant to Gefitinib

Jeffrey A. Engelman, Kreshnik Zejnullahu, Christopher-Michael Gale et al. · Cancer Research · 2007 · 718 citations · Full text

, , +13

Overlapping Roles and Collective Requirement for the Coreceptors GAS1, CDO, and BOC in SHH Pathway Function

Benjamin L. Allen, Jane Y. Song, Luisa Izzi et al. · Developmental Cell · 2011 · 290 citations · Full text

, , +5

Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor

Andrea J. Gonzales, Kenneth E. Hook, Irene W. Althaus et al. · Molecular Cancer Therapeutics · 2008 · 221 citations · Full text

, , +15

Steady-state kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-87201E.

Irene W. Althaus, James J. Chou, Andrea J. Gonzales et al. · Journal of Biological Chemistry · 1993 · 164 citations · Full text

, , +17

The quinoline U-78036 is a potent inhibitor of HIV-1 reverse transcriptase

Irene W. Althaus, Andrea J. Gonzales, James J. Chou et al. · Journal of Biological Chemistry · 1993 · 162 citations · Full text

, , +17

1–5 of 19