Jonathan Tart - Concepedia

Author

Jonathan Tart

AstraZeneca (United Kingdom)

Also Known As

J. Tart, Jonathan Tart

Publications

629

Citations

H-Index

Concepts

All Affiliations

AstraZeneca (United Kingdom)

About

Jonathan Tart is an author at AstraZeneca (United Kingdom) specializing in molecular biology, drug discovery, and chemical biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	3	3	371
2	Natural Sciences	3	3	371
3	Biochemistry	3	3	371
4	Chemical Biology	3	3	371
5	Cell Biology	1	1	84

Jonathan Tart

Publications

603

Citations

H-Index

Page 1

	Year	Citations
Design and Synthesis of Novel Lactate Dehydrogenase A Inhibitors by Fragment-Based Lead Generation Richard A. Ward, C. Brassington, Alexander L. Breeze, Journal of Medicinal Chemistry Aldo-keto ReductaseMolecular BiologyLead IdentificationChemical BiologyMedicinal Chemistry	2012	169
Small Molecule Binding Sites on the Ras:SOS Complex Can Be Exploited for Inhibition of Ras Activation Jon Winter, Malcolm Anderson, Kevin Blades, Journal of Medicinal Chemistry Protein AssemblyMolecular BiologyChemical BiologySos ComplexSmall Molecule Binding	2015	118
Identification and Characterization of Dual Inhibitors of the USP25/28 Deubiquitinating Enzyme Subfamily Jonathan D.J. Wrigley, Gérald Gavory, Iain Simpson, ACS Chemical Biology Aldo-keto ReductaseImmunologyMolecular BiologyUsp28 InhibitionChemical Biology	2017	84
Integrin α5β1 and ADAM-17 Interact in Vitro and Co-localize in Migrating HeLa Cells Daniel V. Bax, Anthea Messent, Jonathan Tart, Journal of Biological Chemistry	2004	80
Mutations in the Interglobular Domain of Aggrecan Alter Matrix Metalloproteinase and Aggrecanase Cleavage Patterns Francesca Mercuri, Rose A. Maciewicz, Jonathan Tart, Journal of Biological Chemistry	2000	53
Matrix metalloproteinase 17 is necessary for cartilage aggrecan degradation in an inflammatory environment Kristen M. Clements, Jo K Flannelly, Jonathan Tart, Annals of the Rheumatic Diseases	2011	35
A TRIM21-based bioPROTAC highlights the therapeutic benefit of HuR degradation Alice Fletcher, Dean Clift, Emma de Vries, Nature Communications	2023	35
Development of a cell-free split-luciferase biochemical assay as a tool for screening for inhibitors of challenging protein-protein interaction targets Rachel Cooley, Neesha Kara, Ning Sze Hui, Wellcome Open Research	2020	29

Page 1