Concepedia

Jonathan D.J. Wrigley

JD

23

Publications

1.3K

Citations

20

H-Index

2000

Active since

Affiliations

MSD (UK) Limited (United Kingdom)(Current)

Merck & Co., Inc., Rahway, NJ, USA (United States)

AstraZeneca (United Kingdom)

University of Leeds

AstraZeneca (Sweden)

Jonathan D.J. Wrigley is an author at MSD (UK) Limited (United Kingdom) specializing in natural sciences, biochemistry, and medicine.

ORCID

Top concepts

Publications per year

2000–2018

23

Publications

23

Selected Non-steroidal Anti-inflammatory Drugs and Their Derivatives Target γ-Secretase at a Novel Site

Dirk Beher, Earl E. Clarke, Jonathan D.J. Wrigley et al. · Journal of Biological Chemistry · 2004 · 178 citations · Full text

BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B

Matthew A. Coelho, Songyuan Li, Luna Simona Pane et al. · BMC Biology · 2018 · 95 citations · Full text

Pharmacological Knock-down of the Presenilin 1 Heterodimer by a Novel γ-Secretase Inhibitor

Dirk Beher, Jonathan D.J. Wrigley, Alan Nadin et al. · Journal of Biological Chemistry · 2001 · 85 citations · Full text

Identification and Characterization of Dual Inhibitors of the USP25/28 Deubiquitinating Enzyme Subfamily

Jonathan D.J. Wrigley, Gérald Gavory, Iain Simpson et al. · ACS Chemical Biology · 2017 · 84 citations · Full text

, , +19

Generation of C‐terminally truncated amyloid‐β peptides is dependent on γ‐secretase activity

Dirk Beher, Jonathan D.J. Wrigley, Andrew P. Owens et al. · Journal of Neurochemistry · 2002 · 82 citations · Full text

, , +15

Rows per page

1–5 of 23