Malcolm Anderson

SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors

Nicola M. Heron, Malcolm Anderson, David P. Blowers et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 125 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Small Molecule Binding Sites on the Ras:SOS Complex Can Be Exploited for Inhibition of Ras Activation

Jon Winter, Malcolm Anderson, Kevin Blades et al. · Journal of Medicinal Chemistry · 2015 · 120 citations

Life Sciences, Biochemistry, Molecular Biology +17

Imidazo[1,2-a]pyridines: A potent and selective class of cyclin-Dependent kinase inhibitors identified through structure-Based hybridisation

Malcolm Anderson, John F. Beattie, Gloria A. Breault et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 114 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +12

Enhanced Detection of Low-Abundance Host Cell Protein Impurities in High-Purity Monoclonal Antibodies Down to 1 ppm Using Ion Mobility Mass Spectrometry Coupled with Multidimensional Liquid Chromatography

Catalin E. Doneanu, Malcolm Anderson, Brad J. Williams et al. · Analytical Chemistry · 2015 · 98 citations · Full text

Life Sciences, Biochemistry, Pharmaceutical Analysis +15

Affinity-based, biophysical methods to detect and analyze ligand binding to recombinant proteins: Matching high information content with high throughput

Geoffrey A. Holdgate, Malcolm Anderson, Fredrik Edfeldt et al. · Journal of Structural Biology · 2010 · 61 citations

Life Sciences, Molecular Biology, Biosensors +14