Concepedia

Imidazo[1,2-a]pyridines: A potent and selective class of cyclin-Dependent kinase inhibitors identified through structure-Based hybridisation

Malcolm Anderson, John F. Beattie, Gloria A. Breault, J. Breed, Kate Byth, Janet D. Culshaw, Rebecca Ellston, Stephen Green, Claire A. Minshull, Richard A. Norman,

Bioorganic & Medicinal Chemistry Letters · 2003 · 114 citations · 20 references

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An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

Robert Esnouf · Journal of Molecular Graphics and Modelling · 1997 · 1.7K citations

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Exploiting Chemical Libraries, Structure, and Genomics in the Search for Kinase Inhibitors

Nathanael S. Gray, Lisa Wodicka, A.M.W.H. Thunnissen et al. · Science · 1998 · 808 citations · Full text

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A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

Liang Tong, Susan Pav, Della White et al. · Nature Structural Biology · 1997 · 386 citations

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Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

Ying-Nan P. Chen, Sushil Sharma, Timothy M. Ramsey et al. · Proceedings of the National Academy of Sciences · 1999 · 319 citations

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Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor

Thomas G. Davies, Johanne Bentley, Christine E. Arris et al. · Nature Structural Biology · 2002 · 214 citations

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