Thomas G. Davies

Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery

Thomas G. Davies, William E. Wixted, Joseph E. Coyle et al. · Journal of Medicinal Chemistry · 2016 · 295 citations · Full text

Molecular Biology, Chemical Biology, Redox Biology +19

Structure of the BTB Domain of Keap1 and Its Interaction with the Triterpenoid Antagonist CDDO

Anne Cleasby, Jeff Yon, Philip J. Day et al. · PLoS ONE · 2014 · 250 citations · Full text

Molecular Biology, Btb Domain, Chemical Biology +17

Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor

Thomas G. Davies, Johanne Bentley, Christine E. Arris et al. · Nature Structural Biology · 2002 · 212 citations

Medicinal Chemistry, Drug Target, Drug Design +6

Evolutionary Trade-Off between Vocal Tract and Testes Dimensions in Howler Monkeys

Jacob C. Dunn, Lauren B. Halenar, Thomas G. Davies et al. · Current Biology · 2015 · 151 citations · Full text

Inhibitor Binding to Active and Inactive CDK2

Thomas G. Davies, Paul Tunnah, Laurent Meijer et al. · Structure · 2001 · 145 citations · Full text

Signal Transduction, Signaling Pathway, Molecular Pathway +4