Precise gene fusion by PCR

Jeff Yon, Mike Fried

Nucleic Acids Research

GeneticsMolecular BiologyTranscriptomics TechnologyMolecular GeneticsReal-time Polymerase Chain Reaction +16

Structure of the BTB Domain of Keap1 and Its Interaction with the Triterpenoid Antagonist CDDO

Anne Cleasby, Jeff Yon, Philip J. Day, +11

PLoS ONE

Molecular BiologyBtb DomainChemical BiologyRedox BiologyProtein Keap1 +15

Crystal structure of human CDK4 in complex with a D-type cyclin

Philip J. Day, Anne Cleasby, Ian J. Tickle, +8

Proceedings of the National Academy of Sciences

Apo and Inhibitor Complex Structures of BACE (β-secretase)

Sahil Patel, Laurent Vuillard, Anne Cleasby, +2

Journal of Molecular Biology

Protein SecretionProtein FunctionInhibitor Complex StructuresBiochemistry

A Human Homologue of the Schizosaccharomyces pombe rad1+ Checkpoint Gene Encodes an Exonuclease

Andrew E. Parker, Inez Van de Weyer, Marc C. Laus, +4

Journal of Biological Chemistry

Structure of a CBS-domain pair from the regulatory γ1 subunit of human AMPK in complex with AMP and ZMP

Philip M. Day, Andrew Sharff, Lina Parra, +7

Acta Crystallographica Section D Biological Crystallography

Amp-activated KinaseMolecular BiologyCellular PhysiologyRegulatory γ1 SubunitHuman Ampk +20

Structure of the Epigenetic Oncogene MMSET and Inhibition by <i>N</i>-Alkyl Sinefungin Derivatives

Dominic Tisi, Elisabetta Chiarparin, Emiliano Tamanini, +21

ACS Chemical Biology

Structural BioinformaticsBiomolecular Structure PredictionEpigenetic ChangeGeneticsMolecular Biology +22

Enovin, a member of the glial cell‐line‐derived neurotrophic factor (GDNF) family with growth promoting activity on neuronal cells

Stefan Masure, Hugo Geerts, Miroslav Cik, +10

European Journal of Biochemistry

Cellular NeurobiologySynaptic SignalingSocial SciencesEnovin Mrna ExpressionTranscriptional Regulation +15

Crystal Structure of Human Soluble Adenylate Cyclase Reveals a Distinct, Highly Flexible Allosteric Bicarbonate Binding Pocket

S. Saalau-Bethell, Valério Berdini, Anne Cleasby, +10

ChemMedChem

Recombinant insect cell expression and purification of human β-secretase (BACE-1) for X-ray crystallography

Wouter Bruinzeel, Jeff Yon, Silvio Giovannelli, +1

Protein Expression and Purification

X-ray CrystallographyProtein SecretionHuman β-SecretaseProtein ExpressionBiochemistry +6