Nicola M. Heron

AZD1152, a Selective Inhibitor of Aurora B Kinase, Inhibits Human Tumor Xenograft Growth by Inducing Apoptosis

Robert W. Wilkinson, Rajesh Odedra, Simon P. Heaton et al. · Clinical Cancer Research · 2007 · 355 citations · Full text

Discovery, Synthesis, and <i>in Vivo</i> Activity of a New Class of Pyrazoloquinazolines as Selective Inhibitors of Aurora B Kinase

Andrew Mortlock, Kevin M. Foote, Nicola M. Heron et al. · Journal of Medicinal Chemistry · 2007 · 270 citations · Full text

Pharmaceutical Science, Selective Inhibitors, Pharmacotherapy +17

SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors

Nicola M. Heron, Malcolm Anderson, David P. Blowers et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 125 citations · Full text

Molecular Docking, Medicine, Natural Sciences +9

Catalytic and Enantioselective Route to Medium-Ring Heterocycles. Asymmetric Zirconium-Catalyzed Ethylmagnesation of Seven- and Eight-Membered Rings

Michael Visser, Nicola M. Heron, Mary T. Didiuk et al. · Journal of the American Chemical Society · 1996 · 112 citations

Eight-membered Rings, Chemical Engineering, Engineering +15

Discovery of Novel and Potent Thiazoloquinazolines as Selective Aurora A and B Kinase Inhibitors

Frédéric Jung, Georges Pasquet, Christine Lambert‐van der Brempt et al. · Journal of Medicinal Chemistry · 2006 · 92 citations · Full text

Planar Conformation, Pharmacotherapy, Selective Aurora A +19