Andrew Mortlock

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

Claire Ditchfield, Victoria Johnson, Anthony Tighe et al. · The Journal of Cell Biology · 2003 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

AZD1152, a Selective Inhibitor of Aurora B Kinase, Inhibits Human Tumor Xenograft Growth by Inducing Apoptosis

Robert W. Wilkinson, Rajesh Odedra, Simon P. Heaton et al. · Clinical Cancer Research · 2007 · 357 citations · Full text

Medicine, Oncology, Pharmacology +16

Discovery, Synthesis, and <i>in Vivo</i> Activity of a New Class of Pyrazoloquinazolines as Selective Inhibitors of Aurora B Kinase

Andrew Mortlock, Kevin M. Foote, Nicola M. Heron et al. · Journal of Medicinal Chemistry · 2007 · 274 citations · Full text

Medicine, Oncology, Pharmacology +13

SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors

Nicola M. Heron, Malcolm Anderson, David P. Blowers et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 125 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Discovery of Novel and Potent Thiazoloquinazolines as Selective Aurora A and B Kinase Inhibitors

Frédéric Jung, Georges Pasquet, Christine Lambert‐van der Brempt et al. · Journal of Medicinal Chemistry · 2006 · 92 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17