Concepedia

Alexander L. Breeze

AL

Statistics

Publications

39

Citations

2.5K

H-Index

26

Active since

1984

Affiliations

AstraZeneca (United Kingdom)(Current)

University of Leeds

Institute of Structural and Molecular Biology

Imperial College London

AstraZeneca (United States)

Alexander L. Breeze is an author at AstraZeneca (United Kingdom) specializing in life sciences, biochemistry, and structural biology.

ORCID

Publications per year

1984–2022

39

Publications

39

Isotope-filtered NMR methods for the study of biomolecular structure and interactions

Alexander L. Breeze · Progress in Nuclear Magnetic Resonance Spectroscopy · 2000 · 203 citations

, , +14

Design and Synthesis of Novel Lactate Dehydrogenase A Inhibitors by Fragment-Based Lead Generation

Richard A. Ward, C. Brassington, Alexander L. Breeze et al. · Journal of Medicinal Chemistry · 2012 · 169 citations · Full text

, , +17

Structure of an SH2 domain of the p85α subunit of phosphatidylinositol-3-OH kinase

Grant W. Booker, Alexander L. Breeze, A. Kristina Downing et al. · Nature · 1992 · 167 citations

, , +16

The high-resolution crystal structure of a 24-kDa gyrase B fragment fromE. coli complexed with one of the most potent coumarin inhibitors, clorobiocin

Francis Tsai, Onkar Singh, Tadeusz Skarżyński et al. · Proteins Structure Function and Bioinformatics · 1997 · 150 citations

, , +10

Pyrrolamide DNA Gyrase Inhibitors: Fragment-Based Nuclear Magnetic Resonance Screening To Identify Antibacterial Agents

Ann E. Eakin, Oluyinka Green, Neil J. Hales et al. · Antimicrobial Agents and Chemotherapy · 2011 · 134 citations

, , +17

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