Onkar Singh

Type IIA topoisomerase inhibition by a new class of antibacterial agents

B.D. Bax, Pan F. Chan, Drake S. Eggleston et al. · Nature · 2010 · 803 citations

Antibacterial Agents, Medicinal Chemistry, Inhibitory Activity +14

Selective Plasma Hydrolysis of Glucocorticoid γ-Lactones and Cyclic Carbonates by the Enzyme Paraoxonase: An Ideal Plasma Inactivation Mechanism

Keith Biggadike, Richard Angell, Colin M. Burgess et al. · Journal of Medicinal Chemistry · 1999 · 180 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +13

The high-resolution crystal structure of a 24-kDa gyrase B fragment fromE. coli complexed with one of the most potent coumarin inhibitors, clorobiocin

Francis Tsai, Onkar Singh, Tadeusz Skarżyński et al. · Proteins Structure Function and Bioinformatics · 1997 · 150 citations

Coumarin Antibiotics, Crystal Structure, High-resolution Crystal Structure +15

Overview of the interactive task in BioCreative V

Wang Qing-hua, Shabbir Syed-Abdul, Lara Almeida et al. · Database · 2016 · 99 citations · Full text

Engineering, Collaborative Information Retrieval, Intelligent Information Retrieval +21

Optimization of Novel Acyl Pyrrolidine Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase Leading to a Development Candidate

Martin J. Slater, Elizabeth M. Amphlett, David Andrews et al. · Journal of Medicinal Chemistry · 2007 · 90 citations

Hcv Replicon, Development Candidate, Molecular Biology +18