Richard Angell

Selective Plasma Hydrolysis of Glucocorticoid γ-Lactones and Cyclic Carbonates by the Enzyme Paraoxonase: An Ideal Plasma Inactivation Mechanism

Keith Biggadike, Richard Angell, Colin M. Burgess et al. · Journal of Medicinal Chemistry · 1999 · 180 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +13

Progress towards a public chemogenomic set for protein kinases and a call for contributions

David H. Drewry, Carrow I. Wells, David Andrews et al. · PLoS ONE · 2017 · 166 citations · Full text

Drug Target, Public Chemogenomic Set, Molecular Biology +17

A small-molecule PI3Kα activator for cardioprotection and neuroregeneration

Grace Q. Gong, Benoît Bilanges, Ben Allsop et al. · Nature · 2023 · 136 citations · Full text

Signal Transduction, Signaling Pathway, Medicine +7

The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors

Sebastian Lambert, David R. Langley, James A. Garnett et al. · Protein Science · 2014 · 99 citations · Full text

Virus Structure, Crystal Structure, Biochemistry +14

N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3

Richard Angell, Francis Atkinson, Murray J. B. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 90 citations · Full text

Medicinal Chemistry, Medicine, Rational Drug Design +4