Grace Q. Gong

A small-molecule PI3Kα activator for cardioprotection and neuroregeneration

Grace Q. Gong, Benoît Bilanges, Ben Allsop et al. · Nature · 2023 · 136 citations · Full text

Signal Transduction, Signaling Pathway, Medicine +7

Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function

Manojit Mosur Swamynathan, Shan Kuang, Kaitlin Watrud et al. · Science · 2024 · 34 citations · Full text

A single discrete Rab5-binding site in phosphoinositide 3-kinase β is required for tumor cell invasion

Samantha D. Heitz, David Hamelin, Reece M. Hoffmann et al. · Journal of Biological Chemistry · 2019 · 16 citations · Full text

High-throughput screening campaigns against a PI3Kα isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds

Jia Wang, Grace Q. Gong, Yan Zhou et al. · Acta Pharmacologica Sinica · 2018 · 14 citations · Full text

Molecular Docking, Engineering, Pi3kα Isoform +10

Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds

Grace Q. Gong, Ke Wang, Xinchuan Dai et al. · Acta Pharmacologica Sinica · 2018 · 13 citations · Full text

Molecular Docking, Medicinal Chemistry, Natural Sciences +11