Ann E. Eakin

The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi.

Ann E. Eakin, Alea A. Mills, G Harth et al. · Journal of Biological Chemistry · 1992 · 291 citations · Full text

The Crystal Structure of Cruzain: A Therapeutic Target for Chagas' Disease

Mary E. McGrath, Ann E. Eakin, Juan C. Engel et al. · Journal of Molecular Biology · 1995 · 266 citations

Crystal Structure, Biochemistry, Natural Sciences +4

Pyrrolamide DNA Gyrase Inhibitors: Fragment-Based Nuclear Magnetic Resonance Screening To Identify Antibacterial Agents

Ann E. Eakin, Oluyinka Green, Neil J. Hales et al. · Antimicrobial Agents and Chemotherapy · 2011 · 132 citations

Essential Enzyme, Lead Identification, Antimicrobial Chemotherapy +18

Pyrrolamide DNA gyrase inhibitors: Optimization of antibacterial activity and efficacy

Brian Sherer, Kenneth G. Hull, Oluyinka Green et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 119 citations · Full text

Inhibitory Activity, Medicinal Chemistry, Medicine +10

Serine proteases from nematode and protozoan parasites: isolation of sequence homologs using generic molecular probes.

Judy A. Sakanari, Catherine E. Staunton, Ann E. Eakin et al. · Proceedings of the National Academy of Sciences · 1989 · 117 citations · Full text

Parasitic Disease, Protozoan Parasites, Biochemistry +14