Concepedia

The Crystal Structure of Cruzain: A Therapeutic Target for Chagas' Disease

Mary E. McGrath, Ann E. Eakin, Juan C. Engel, James H. McKerrow, Charles S. Craik, Robert J. Fletterick

Journal of Molecular Biology · 1995 · 268 citations · 0 references

Concepts

Life SciencesBiochemistryMolecular BiologyDrug DesignDrug DiscoveryStructural BiologyChagas DiseaseCrystal ChemistryParasitic Disease PathogenesisProtozoan PathogenesisCrystal Structure RefinementTherapeutic Target IdentificationTherapeutic Target ValidationTrypanosoma Cruzi Infection