Becky Sargent

Discovery of SB-705498: A potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development

Harshad K. Rami, Mervyn Thompson, Geoffrey Stemp et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 132 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +5

Investigation into the role of P2X₃/P2X_2/3 receptors in neuropathic pain following chronic constriction injury in the rat: an electrophysiological study

Caroline J Sharp, Alison J. Reeve, S D Collins et al. · British Journal of Pharmacology · 2006 · 65 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Structurally novel histamine H3 receptor antagonists GSK207040 and GSK334429 improve scopolamine-induced memory impairment and capsaicin-induced secondary allodynia in rats

Andrew D. Medhurst, Michael A. Briggs, Gordon Bruton et al. · Biochemical Pharmacology · 2007 · 64 citations

Life Sciences, Neuroscience, Pharmacology +12

The Cyclooxygenase-2 Inhibitor GW406381X [2-(4-Ethoxyphenyl)-3-[4-(methylsulfonyl)phenyl]-pyrazolo[1,5-b]pyridazine] Is Effective in Animal Models of Neuropathic Pain and Central Sensitization

Sharon Bingham, Paul Beswick, C. Bountra et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 63 citations

Medicine, Pharmacology, Pharmacotherapy +17

Use of dynamic weight bearing as a novel end-point for the assessment of Freund's Complete Adjuvant induced hypersensitivity in mice

Ian Robinson, Becky Sargent, Jon P. Hatcher · Neuroscience Letters · 2012 · 37 citations

Life Sciences, Immunology, Hypersensitivity +6