Gordon Bruton

Inhibitors of Bacterial Signal Peptidases

M. BLACK, Gordon Bruton · Current Pharmaceutical Design · 1970 · 65 citations

Bioorganic Chemistry, Antimicrobial Chemotherapy, Chemical Biology +21

Structurally novel histamine H3 receptor antagonists GSK207040 and GSK334429 improve scopolamine-induced memory impairment and capsaicin-induced secondary allodynia in rats

Andrew D. Medhurst, Michael A. Briggs, Gordon Bruton et al. · Biochemical Pharmacology · 2007 · 64 citations

Scopolamine-induced Memory Impairment, Medicine, Behavioural Pharmacology +7

Lipopeptide substrates for SpsB, the Staphylococcus aureus type I signal peptidase: design, conformation and conversion to α-ketoamide inhibitors

Gordon Bruton, Anthony Huxley, Peter J. O’Hanlon et al. · European Journal of Medicinal Chemistry · 2003 · 52 citations

α-Ketoamide Inhibitors, Signal Peptidase, Antimicrobial Drug Discovery +10

6-(Substituted methylene)penems, potent broad spectrum inhibitors of bacterial .BETA.-lactamase. III. Structure-activity relationships of the 5-membered heterocyclic derivatives.

ISABEL S. BENNETT, N. J. P. BROOM, Gordon Bruton et al. · The Journal of Antibiotics · 1991 · 44 citations · Full text

An efficient synthesis of endo,exo-furofuranone derivatives

Nigel A. Swain, Richard C. D. Brown, Gordon Bruton · Chemical Communications · 2002 · 23 citations

Exo-furofuranone Derivatives, Heterocyclic, Ring Openings +8